Interpreting Gel Electrophoresis

Interpreting Gel Electrophoresis

Grade 14 ¡ Science ¡ 50 min

What's Included

Learning Objective

I can interpret gel electrophoresis results to draw conclusions about DNA samples.

Warm-Up Video

Amoeba Sisters ¡ 7:55

Gel Electrophoresis

Guided Notes

3 key concepts

  • 1

    Gel electrophoresis separates molecules, especially DNA, based on their size and charge.

  • 2

    Restriction enzymes are used to cut DNA into fragments at specific sequences, and these fragments are then loaded into the wells of the gel.

  • 3

    DNA bands can be compared to a DNA ladder, which contains fragments of known sizes, to estimate the size of unknown DNA fragments and determine relatedness between samples.

Practice Questions

11 questions ¡ Multiple choice & Short answer

Exit Ticket

Quick comprehension check

“A gel electrophoresis is run on four DNA samples. Sample 1, Sample 2, and Sample 3 are from different individuals. Sample 4 is a DNA ladder with known fragment sizes. After running the gel, the banding patterns for Samples 1 and 3 appear most similar. What can you conclude about the relationship between the individuals who provided Sample 1 and Sample 3?”

Complete Lesson Package

Get all 3 ready-to-use resources:

Teacher Guide
Student Doc
Slides